The verdict

Plex
Intel QuickSync (UHD Gen12 iGPU) transcodes video; Google M.2 Accelerator A+E key is detection-only (no transcode).
Frigate
Intel QuickSync (UHD Gen12 iGPU) handles more cameras (~25 vs ~5).
Fit
Google M.2 Accelerator A+E key is easier to add to a mini-PC (M.2, needs a spare slot).

Which wins for each job

Job Google M.2 Accelerator A+E key Intel QuickSync (UHD Gen12 iGPU)
Plex transcode none ~8 streams win
Frigate NVR ~5 cameras ~25 cameras win
Local LLM none none
Fits a mini-PC M.2, needs a spare slot win built into a CPU

Approximate - capacity estimates from curated specs, the same logic as the recommender. Verify against your exact setup. Prices move; check the retailer.

Full specs

Spec Google M.2 Accelerator A+E key Intel QuickSync (UHD Gen12 iGPU)
Price (list) $30 -
Type tpu igpu
Interface m2-ae built-in
Transcode - H.264/HEVC 4K (AV1 decode)
Frigate detector EdgeTPU (native) OpenVINO
TOPS 4 -
VRAM (GB) - -
Low profile no no
GPU sharing - sr-iov
Power (W) 2 0